The LDL Receptor Defect in Familial Hypercholesterolemia: Implications for Pathogenesis and Therapy

Author:

Goldstein Joseph L.,Brown Michael S.

Publisher

Elsevier BV

Subject

General Medicine

Reference93 articles.

1. Mevinolin, a highly potent competitive inhibitor of HMG-CoA reductase and cholesterol lowering agent;Alberts;Proc. Natl. Acad. Sci. USA,1980

2. Regulation of sterol synthesis in 15 tissues of rat. II. Role of rat and human high and low density plasma lipoproteins and of rat chylomicron remnants;Andersen;J. Biol. Chem,1977

3. Evidence for regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol synthesis in nonhepatic tissues of rat;Balasubramaniam;Proc. Natl. Acad. Sci. USA,1976

4. Degradation of low density lipoprotein-dextran sulfate complexes associated with deposition of cholesteryl esters in mouse macrophages;Basu;J. Biol. Chem,1979

5. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts;Basu;Proc. Natl. Acad. Sci. USA,1976

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