Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Author:

Lipinski Christopher A.,Lombardo Franco,Dominy Beryl W.,Feeney Paul J.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference50 articles.

1. Strategies and recent technologies in drug discovery;Kubinyi;Pharmazie,1995

2. Chapter 33. Recent Advances in the Generation of Molecular Diversity;Moos;Annu. Rep. Med. Chem.,1993

3. Applications of small-molecule combinatorial chemistry to drug discovery;Patel;Drug Discov. Today,1996

4. Combinatorial approaches provide fresh leads for medicinal chemistry;Baum;Chem. Eng. News,1994

5. Using backpropagation networks for the estimation of aqueous activity coefficients of aromatic compounds;Chow;J. Chem. Inf. Comput. Sci.,1995

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