Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters
Author:
Funder
National Institutes of Health
Publisher
Elsevier BV
Subject
Virology,Pharmacology
Reference41 articles.
1. Brincidofovir: understanding its unique profile and potential role against adenovirus and other viral infections;Alvarez-Cardona;Future Microbiol.,2020
2. Animal models in human adenovirus research;Bertzbach;Biology,2021
3. Cidofovir diphosphate inhibits adenovirus 5 DNA polymerase via both non-obligate chain termination and direct inhibition, and polymerase mutations confer cidofovir resistance on intact virus;Chamberlain;Antimicrob. Agents Chemother.63,2018
4. Brincidofovir (CMX001) toxicity associated with epithelial apoptosis and crypt drop out in a hematopoietic cell transplant patient: challenges in distinguishing drug toxicity from GVHD;Detweiler;J. Pediatr. Hematol. Oncol.,2018
5. Emerging antiviral therapeutics for human adenovirus infection: recent developments and novel strategies;Dodge;Antivir. Res.,2021
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