Expanding the anti-flaviviral arsenal: Discovery of a baicalein-derived Compound with potent activity against DENV and ZIKV.

Author:

Putri Geraldine NadyaORCID,Gudla Chandra Sekhar,Singh Mayas,Ng Chin HuanORCID,Idris Fakhriedzwan Fitri HajiORCID,Oo YukeiORCID,Tan Jasmine Hwee Yee,Wong Joel Feng Jie,Chu Justin Jang HannORCID,Selvam VigneshORCID,Selvaraj Siva Shanmugam,Shandil Radha Krishan,Narayanan ShridharORCID,Alonso SylvieORCID

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference40 articles.

1. NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models;A;Sci. Transl. Med.,2021

2. M2 protein-A proton channel of influenza A virus;Betakova;Curr. Pharmaceut. Des.,2007

3. The global distribution and burden of dengue;Bhatt;Nature,2013

4. The 8-bromobaicalein inhibited the replication of dengue, and Zika viruses and targeted the dengue polymerase;Boonyasuppayakorn;Sci. Rep.,2023

5. Pharmacological potential of flavonoids against neurotropic viruses;Castro E Silva;Pharmaceuticals,2022

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