A Cell-Permeable Inhibitor to Trap Gαq Proteins in the Empty Pocket Conformation-Reference-Cited by-同舟云学术

A Cell-Permeable Inhibitor to Trap Gαq Proteins in the Empty Pocket Conformation

Published:2014-07 Issue:7 Volume:21 Page:890-902
ISSN:1074-5521
Container-title:Chemistry & Biology
language:en
Short-container-title:Chemistry & Biology

Author:

Schmitz Anna-Lena,Schrage Ramona,Gaffal Evelyn,Charpentier Thomas H.,Wiest Johannes,Hiltensperger Georg,Morschel Julia,Hennen Stephanie,Häußler Daniela,Horn Velten,Wenzel Daniela,Grundmann Manuel,Büllesbach Katrin M.,Schröder Ralf,Brewitz H. Henning,Schmidt Johannes,Gomeza Jesús,Galés Céline,Fleischmann Bernd K.,Tüting Thomas,Imhof Diana,Tietze Daniel,Gütschow Michael,Holzgrabe Ulrike,Sondek John,Harden T. Kendall,Mohr Klaus,Kostenis Evi

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

Reference34 articles.

1. Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2;Ahmed-Belkacem;Cancer Res.,2005

2. Acetylcholine analogue stimulates DNA synthesis in brain-derived cells via specific muscarinic receptor subtypes;Ashkenazi;Nature,1989

3. Inhibition of heterotrimeric G protein signaling by a small molecule acting on Galpha subunit;Ayoub;J. Biol. Chem.,2009

4. Differential targeting of Gbetagamma-subunit signaling with small molecules;Bonacci;Science,2006

5. Kinetic control of guanine nucleotide binding to soluble Galpha(q);Chidiac;Biochem. Pharmacol.,1999

Cited by 48 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Strategies that regulate Hippo signaling pathway for novel anticancer therapeutics;European Journal of Medicinal Chemistry;2024-10

2. In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G_q‐Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont;Angewandte Chemie;2024-02-02

3. In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G_q‐Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont;Angewandte Chemie International Edition;2024-02-02

4. RGS2 is an innate immune checkpoint for TLR4 and Gαq-mediated IFNγ generation and lung injury;2023-09-23

5. Calnuc‐derived nesfatin‐1‐like peptide is an activator of tumor cell proliferation and migration;FEBS Letters;2023-08-13