Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling-Reference-Cited by-同舟云学术

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

Published:2024-07 Issue:7 Volume:31 Page:1247-1263.e16
ISSN:2451-9456
Container-title:Cell Chemical Biology
language:en
Short-container-title:Cell Chemical Biology

Author:

Graham Keith,Lienau Philip,Bader Benjamin,Prechtl Stefan,Naujoks Jan,Lesche Ralf,Weiske Joerg,Kuehnlenz Julia,Brzezinka Krzysztof,Potze Lisette,Zanconato Francesca,Nicke Barbara,Montebaur Anna,Bone Wilhelm,Golfier Sven,Kaulfuss Stefan,Kopitz Charlotte,Pilari Sabine,Steuber Holger,Hayat Sikander,Kamburov Atanas,Steffen Andreas,Schlicker Andreas,Buchgraber Philipp,Braeuer Nico,Font Nuria Aiguabella,Heinrich Tobias,Kuhnke Lara,Nowak-Reppel Katrin,Stresemann Carlo,Steigemann Patrick,Walter Annette O.,Blotta Simona,Ocker Matthias,Lakner Ashley,von Nussbaum Franz,Mumberg Dominik,Eis Knut,Piccolo Stefano,Lange Martin^ORCID

Publisher

Elsevier BV

Reference99 articles.

1. Elucidation of a universal size-control mechanism in Drosophila and mammals;Dong;Cell,2007

2. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP;Huang;Cell,2005

3. TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins;Kanai;EMBO J.,2000

4. Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product;Sudol;Oncogene,1994

5. The hippo tumor pathway promotes TAZ degradation by phosphorylating a phosphodegron and recruiting the SCF{beta}-TrCP E3 ligase;Liu;J. Biol. Chem.,2010

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. YAP/TAZ Signaling in the Pathobiology of Pulmonary Fibrosis;Cells;2024-09-10