The transition between active and inactive conformations of Abl kinase studied by rock climbing and Milestoning-Reference-Cited by-同舟云学术

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The transition between active and inactive conformations of Abl kinase studied by rock climbing and Milestoning

Published:2020-04 Issue:4 Volume:1864 Page:129508
ISSN:0304-4165
Container-title:Biochimica et Biophysica Acta (BBA) - General Subjects
language:en
Short-container-title:Biochimica et Biophysica Acta (BBA) - General Subjects

Author:

Narayan Brajesh,Fathizadeh Arman,Templeton Clark,He Peng,Arasteh Shima,Elber Ron,Buchete Nicolae-Viorel,Levy Ron M.

Funder

NIH

Welch

Thomas Preston Ph.D. Scholarship Fund

European Union's Horizon 2020

NanoinformaTIX

Publisher

Elsevier BV

Subject

Molecular Biology,Biochemistry,Biophysics

Reference46 articles.

1. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia;Druker;N. Engl. J. Med.,2001

2. Protein kinases - the major drug targets of the twenty-first century?;Cohen;Nat. Rev. Drug Discov.,2002

3. Structural basis of inhibitor selectivity in MAP kinases;Wang;Structure,1998

4. Energetic dissection of Gleevec’s selectivity toward human tyrosine kinases;Agafonov;Nat. Struct. Mol. Biol.,2014

5. The conformational plasticity of protein kinases;Huse;Cell,2002

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1. Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases;Nature Communications;2024-08-02

2. Compound Mutations in the Abl1 Kinase Cause Inhibitor Resistance by Shifting DFG Flip Mechanisms and Relative State Populations;2024-05-26

3. Classifying protein kinase conformations with machine learning;Protein Science;2024-03-19

4. Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases;2024-03-12

5. Exploring Kinase Asp-Phe-Gly (DFG) Loop Conformational Stability with AlphaFold2-RAVE;Journal of Chemical Information and Modeling;2023-11-20

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