An Optical Coherence Tomography-Guided, Variable Dosing Regimen with Intravitreal Ranibizumab (Lucentis) for Neovascular Age-related Macular Degeneration

Author:

Fung Anne E.,Lalwani Geeta A.,Rosenfeld Philip J.,Dubovy Sander R.,Michels Stephan,Feuer William J.,Puliafito Carmen A.,Davis Janet L.,Flynn Harry W.,Esquiabro Maria

Publisher

Elsevier BV

Subject

Ophthalmology

Reference8 articles.

1. VEGF Inhibition Study in Ocular Neovascularization Clinical Trial Group;Gragoudas;N Engl J Med,2004

2. Ranibizumab for neovascular age-related macular degeneration;Rosenfeld;N Engl J Med,2006

3. Ranibizumab vs verteporfin for neovascular age-related macular degeneration;Brown;N Engl J Med,2006

4. Preliminary results from a phase IIIb study showed patients with wet AMD treated with Lucentis quarterly experienced a 16-letter benefit over the control group at one year. [press release]. South San Francisco, California: Genentech; June 2, 2006. Available at: http://www.gene.com/gene/news/press-releases/display.do?method=detail&id=9747. Accessed Date: August 26, 2006.

5. Selection and analysis of an optimized anti-VEGF antibody: crystal structure of an affinity-matured Fab in complex with antigen;Chen;J Mol Biol,1999

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