CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response-Reference-Cited by-同舟云学术

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CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response

Published:2019-03 Issue:3 Volume:35 Page:473-488.e6
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Kuhn Nicholas F.,Purdon Terence J.,van Leeuwen Dayenne G.,Lopez Andrea V.,Curran Kevin J.,Daniyan Anthony F.,Brentjens Renier J.

Funder

National Cancer Institute

National Institutes of Health

The Annual Terry Fox Run for Cancer Research

Kate’s Team

Cabot Family Charitable Trust

Leukemia and Lymphoma Society

William Lawrence and Blanche Hughes Foundation

Emerald Foundation

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference59 articles.

1. Engineered tumor-targeted T cells mediate enhanced anti-tumor efficacy both directly and through activation of the endogenous immune system;Avanzi;Cell Rep.,2018

2. Dendritic cells and the control of immunity;Banchereau;Nature,1998

3. Two lymph nodes draining the mouse liver are the preferential site of DC migration and T cell activation;Barbier;J. Hepatol.,2012

4. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans;Beatty;Science,2011

5. A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma;Beatty;Clin. Cancer Res.,2013

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