DOTting the Path to Doom: How Acceleration of Histone Methylation Leads to Leukemia
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Cell Biology,Oncology
Reference9 articles.
1. MLL-Rearranged Leukemia Is Dependent on Aberrant H3K79 Methylation by DOT1L
2. AF10 Regulates Progressive H3K79 Methylation and HOX Gene Expression in Diverse AML Subtypes
3. The Histone H3K79 Methyltransferase Dot1L Is Essential for Mammalian Development and Heterochromatin Structure
4. AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia
5. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. DNA methylation of HOX genes and its clinical implications in cancer;Experimental and Molecular Pathology;2023-12
2. Activation of the Lysosome-Associated Membrane Protein LAMP5 by DOT1L Serves as a Bodyguard for MLL Fusion Oncoproteins to Evade Degradation in Leukemia;Clinical Cancer Research;2019-01-16
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