Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems

Author:

Bellwon P.,Truisi G.L.,Bois F.Y.,Wilmes A.,Schmidt T.,Savary C.C.,Parmentier C.,Hewitt P.G.,Schmal O.,Josse R.,Richert L.,Guillouzo A.,Mueller S.O.,Jennings P.,Testai E.,Dekant W.

Funder

European Union’s 7th Framework Program

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference76 articles.

1. Plateable cryopreserved human hepatocytes for the assessment of cytochrome P450 inducibility: experimental condition-related variables affecting their response to inducers;Alexandre;Xenobiotica,2012

2. Cyclosporine A- and tacrolimus-mediated inhibition of CYP3A4 and CYP3A5 in vitro;Amundsen;Drug Metab. Dispos.,2012

3. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells;Aninat;Drug Metab. Dispos.,2006

4. Atkinson, K., Biggs, J., Dodds, A., Concannon, A., 1983. Cyclosporine-associated hepatotoxicity after allogeneic marrow transplantation in man: differentiation from other causes of posttransplant liver disease. In: Conference. Transplantation Proceedings.

5. Toxicokinetics in preclinical evaluation;Baldrick;Drug Discov. Today,2003

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