Role of carboxyl terminus of μ- and δ-opioid receptor in agonist -induced down-regulation

Author:

Afify Elham A,Law Ping Y,Riedl Maureen,Elde Robert,Loh Horace H

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Reference36 articles.

1. Distribution and targeting of a μ-opioid receptor (MOR1) in brain and spinal cord;Arvidsson;J. Neurosci.,1995

2. A highly conserved tyrosine residue in G-protein-coupled receptors is required for agonist-mediated β2-adrenergic receptor sequestration;Barak;J. Biol. Chem.,1994

3. Phosphorylation of the mammalian β-adrenergic receptor by cyclic AMP-dependent protein kinase;Benovic;J. Biol. Chem.,1985

4. Neuroblastoma Neuro 2A cells stably expressing a cloned μ-opioid receptor: a specific cellular model to study acute and chronic effects of morphine;Chakrabarti;Mol. Brain Res.,1995

5. S. Chakraberti, W. Yang, P.-Y. Law, H. Loh, The μ-opioid receptor down-regulates differently from the δ-opioid receptor: requirement of a high affinity receptor-G-protein complex formation, Mol. Pharmacol., in press (1997).

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