Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability-Reference-Cited by-同舟云学术

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Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability

Published:2024-02 Issue: Volume:100 Page:117588
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Yang Hwasun,Kang Miso,Jang Seonyeong,Baek Soo Yeon,Kim Jiwon,Kim Gyeong Un,Kim Dongwoo^ORCID,Ha Junsu,Kim Jong Seung,Jung Cheulhee,Kim Nam-Jung,Cho Sung-Yup,Shin Woong-Hee^ORCID,Lee Juyong,Ko Junsu,Lee Ansoo,Keum Gyochang^ORCID,Lee Sanghee^ORCID,Kang Taek^ORCID

Funder

National Research Foundation of Korea

Ministry of Environment

Ministry of Science, ICT and Future Planning

Korea Environmental Industry and Technology Institute

Korea Institute of Science and Technology

Publisher

Elsevier BV

Reference49 articles.

1. Microsatellite instability: a review of what the oncologist should know;Li;Cancer Cell International,2020

2. Microsatellite instability in human solid tumors;Arzimanoglou;Cancer,1998

3. Landscape of microsatellite instability across 39 cancer types;Bonneville;JCO Precision Oncology,2017

4. Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade;Le;Science,2017

5. Hallmarks of response, resistance, and toxicity to immune checkpoint blockade;Morad;Cell,2022

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