Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration-Reference-Cited by-同舟云学术

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Identification of Ebselen derivatives as novel SARS-CoV-2 main protease inhibitors: Design, synthesis, biological evaluation, and structure-activity relationships exploration

Published:2023-12 Issue: Volume:96 Page:117531
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Zhang Heng^ORCID,Li Jing,Toth Karoly,Tollefson Ann E.,Jing Lanlan,Gao Shenghua,Liu Xinyong^ORCID,Zhan Peng^ORCID

Funder

NSFC

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference34 articles.

1. World Health Organization. WHO Coronavirus (COVID-19) Dashboard. [last cited: [August 02, 2023]].

2. SARS-CoV-2 variants, spike mutations and immune escape;Harvey;Nat Rev Microbiol,2021

3. Coronavirus biology and replication: implications for SARS-CoV-2;V'Kovski;Nat Rev Microbiol,2021

4. Structural biology of SARS-CoV-2 and implications for therapeutic development;Yang;Nat Rev Microbiol,2021

5. Discovery of ketone-based covalent inhibitors of coronavirus 3CL proteases for the potential therapeutic treatment of COVID-19;Hoffman;J Med Chem,2020

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