Peripheral site ligand–oxime conjugates: A novel concept towards reactivation of nerve agent-inhibited human acetylcholinesterase-Reference-Cited by-同舟云学术

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Peripheral site ligand–oxime conjugates: A novel concept towards reactivation of nerve agent-inhibited human acetylcholinesterase

Published:2011-01 Issue:1 Volume:19 Page:588-594
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

de Koning M.C.,Joosen M.J.A.,Noort D.,van Zuylen A.,Tromp M.C.

Funder

Dutch Ministry of Defence

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference36 articles.

1. Atomic Structure of Acetylcholinesterase from Torpedo californica : A Prototypic Acetylcholine-Binding Protein

2. Role of Aspartate 70 and Tryptophan 82 in Binding of Succinyldithiocholine to Human Butyrylcholinesterase

3. Substrate Binding to the Peripheral Site of Acetylcholinesterase Initiates Enzymatic Catalysis. Substrate Inhibition Arises as a Secondary Effect

4. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states

5. Organophosphate poisoning

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1. The risk associated with organophosphorus nerve agents: from their discovery to their unavoidable threat, current medical countermeasures and perspectives;Chemico-Biological Interactions;2024-05

2. Screening of efficient salicylaldoxime reactivators for DFP and paraoxon-inhibited acetylcholinesterase;RSC Medicinal Chemistry;2024

3. Screening of Efficient Salicylaldoxime Reactivators for DFP and Paraoxon-Inhibited Acetylcholinesterase;2023

4. Synthesis and evaluation of small organic molecule as reactivator of organophosphorus inhibited acetylcholinesterase;Drug and Chemical Toxicology;2022-12-14

5. Discovery of Novel Non-Oxime Reactivators Showing In Vivo Antidotal Efficiency for Sarin Poisoned Mice;Molecules;2022-02-07

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