Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy
Author:
Funder
European Research Council
Publisher
Elsevier BV
Subject
Cancer Research,Oncology
Reference84 articles.
1. Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscura;Dobzhansky;Genetics,1946
2. Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions;Han;Nat. Biotechnol.,2017
3. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy;Farmer;Nature,2005
4. Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase.[erratum appears in Nature. 2007 May 17;447(7142):346];Bryant;Nature,2005
5. DNA polymerase θ is preferentially expressed in lymphoid tissues and upregulated in human cancers;Kawamura;Int. J. Cancer,2004
Cited by 110 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Talazoparib enhances resection at DSBs and renders HR-proficient cancer cells susceptible to Polθ inhibition;Radiotherapy and Oncology;2024-11
2. Current status and prospect of the DNA double-strand break repair pathway in colorectal cancer development and treatment;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-10
3. "Bridging the DNA divide": Understanding the interplay between replication- gaps and homologous recombination proteins RAD51 and BRCA1/2;DNA Repair;2024-09
4. A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution;2024-08-27
5. Polθ Inhibitor (ART558) Demonstrates a Synthetic Lethal Effect with PARP and RAD52 Inhibitors in Glioblastoma Cells;International Journal of Molecular Sciences;2024-08-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3