Safety, efficacy and tolerability of half-dose sofosbuvir plus simeprevir in treatment of Hepatitis C in patients with end stage renal disease

Author:

Kalyan Ram Bhamidimarri,Frank Czul,Adam Peyton,Cynthia Levy,Maria Hernandez,Lennox Jeffers,David Roth,Eugene Schiff,Christopher O’Brien,Paul Martin

Publisher

Elsevier BV

Subject

Hepatology

Reference15 articles.

1. EASL recommendations on treatment of hepatitis C 2014;J Hepatol,2014

2. AASLD, IDSA Recommendations for testing, managing and treating Hepatitis C. (accessed March 4th 2015).

3. Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment naıve patients with genotypes 1, 2, and 3 hepatitis C infection: a randomized, double-blind, phase 2 trial;Lawitz;Lancet Infect Dis,2013

4. Anti-viral efficacy and pharmacokinetics (PK) of Sofosbuvir (SOF) in patients with severe renal impairment;Gane;Hepatology,2014

5. Pharmacokinetics, safety and tolerability of GS-9851, a nucleotide analog polymerase inhibitor for hepatitis C virus, following single ascending doses in healthy subjects;Denning;Antimicrob Agents Chemother,2013

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