Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity

Author:

Fitzel Rahel,Secker-Grob Kathy-Ann,Keppeler HildegardORCID,Korkmaz Fulya,Schairer Rebekka,Erkner Estelle,Schneidawind Dominik,Lengerke Claudia,Hentrich ThomasORCID,Schulze-Hentrich Julia M.ORCID,Schneidawind CorinaORCID

Publisher

Elsevier BV

Subject

Cancer Research

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3. Combined effects of the two reciprocal t(4;11) fusion proteins MLL.AF4 and AF4.MLL confer resistance to apoptosis, cell cycling capacity and growth transformation;Gaussmann;Oncogene,2007

4. Risk of infection in elderly patients with AML and MDS treated with hypomethylating agents;Livio;Acta Biomed.,2018

5. Inhibition of DOT1L and PRMT5 promote synergistic anti-tumor activity in a human MLL leukemia model induced by CRISPR/Cas9;Secker;Oncogene,2019

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