Fixed Versus Variable Dosing of Prothrombin Complex Concentrate for Bleeding Complications of Vitamin K Antagonists—The PROPER3 Randomized Clinical Trial

Author:

Abdoellakhan Rahat A.,Khorsand Nakisa,ter Avest Ewoud,Lameijer Heleen,Faber Laura M.,Ypma Paula F.,Nieuwenhuizen Laurens,Veeger Nic J.G. M.,Meijer Karina

Publisher

Elsevier BV

Subject

Emergency Medicine

Reference18 articles.

1. American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy;Witt;Blood Adv,2018

2. 2020 ACC Expert Consensus decision pathway on management of bleeding in patients on oral anticoagulants: a report of the American College of Cardiology Solution Set Oversight Committee;Tomaselli;J Am Coll Cardiol,2020

3. Cofact (human prothrombin complex) product monograph. Medicines Evaluation Board CBG-MEB. https://www.geneesmiddeleninformatiebank.nl/smpc/h17060_smpc.pdf. Accessed September 1, 2020.

4. Beriplex P/N (human prothrombin complex) product monograph. Medicines Evaluation Board CBG-MEB. https://www.geneesmiddeleninformatiebank.nl/smpc/h101080_smpc.pdf. Accessed September 1, 2020.

5. Fixed versus variable dose of prothrombin complex concentrate for counteracting vitamin K antagonist therapy;Khorsand;Transfus Med,2011

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