CD8+ T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy
Author:
Funder
Genentech
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology
Reference73 articles.
1. Hallmarks of response, resistance, and toxicity to immune checkpoint blockade;Morad;Cell,2021
2. IL-6 as a keystone cytokine in health and disease;Hunter;Nat. Immunol.,2015
3. Interleukin-6: biology, signaling and strategies of blockade;Schaper;Cytokine Growth Factor Rev.,2015
4. Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer;Jones;Nat. Rev. Immunol.,2018
5. Combined blockade of IL6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment;Tsukamoto;Cancer Res.,2018
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