Unbiased targeted next-generation sequencing molecular approach for primary immunodeficiency diseases

Author:

Al-Mousa Hamoud,Abouelhoda Mohamed,Monies Dorota M.,Al-Tassan Nada,Al-Ghonaium Abdulaziz,Al-Saud Bandar,Al-Dhekri Hasan,Arnaout Rand,Al-Muhsen Saleh,Ades Nazema,Elshorbagi Sahar,Al Gazlan Sulaiman,Sheikh Farrukh,Dasouki Majed,El-Baik Lina,Elamin Tanzeil,Jaber Amal,Kheir Omnia,El-Kalioby Mohamed,Subhani Shazia,Al Idrissi Eman,Al-Zahrani Mofareh,Alhelale Maryam,Alnader Noukha,Al-Otaibi Afaf,Kattan Rana,Al Abdelrahman Khalid,Al Breacan Muna M.,Bin Humaid Faisal S.,Wakil Salma Majid,Alzayer Fadi,Al-Dusery Haya,Faquih Tariq,Al-Hissi Safa,Meyer Brian F.,Hawwari Abbas

Funder

National Plan for Science, Technology and Innovation

King Abdulaziz City for Science and Technology

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference24 articles.

1. Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency;Al-Herz;Front Immunol,2014

2. Is it necessary to identify molecular defects in primary immunodeficiency disease?;Notarangelo;J Allergy Clin Immunol,2008

3. Omenn syndrome: inflammation in leaky severe combined immunodeficiency;Villa;J Allergy Clin Immunol,2008

4. The genetic and biochemical basis of Omenn syndrome;Santagata;Immunol Rev,2000

5. V(D)J recombination defects in lymphocytes due to RAG mutations: severe immunodeficiency with a spectrum of clinical presentations;Villa;Blood,2001

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