NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity

Author:

Moecking Jonas,Laohamonthonkul Pawat,Chalker Katelyn,White Marquitta J.,Harapas Cassandra R.,Yu Chien-Hsiung,Davidson Sophia,Hrovat-Schaale Katja,Hu Donglei,Eng Celeste,Huntsman Scott,Calleja Dale J.,Horvat Jay C.,Hansbro Phil M.,O’Donoghue Robert J.J.,Ting Jenny P.,Burchard Esteban G.,Geyer Matthias,Gerlic Motti,Masters Seth L.

Funder

National Heart, Lung, and Blood Institute

Veski

Wellcome Trust

Alpha-1 Foundation

National Institutes of Health

Robert Wood Johnson Foundation

National Institute on Minority Health and Health Disparities

National Health and Medical Research Council

Israel Science Foundation

Deutsche Forschungsgemeinschaft

Health and Environmental Sciences Institute

Sandler Foundation

National Human Genome Research Institute

Sylvia and Charles Viertel Charitable Foundation

Publisher

Elsevier BV

Subject

Immunology,Immunology and Allergy

Reference94 articles.

1. Viral respiratory infections and asthma: the course ahead;Dimitrova;PLoS One,2017

2. Rule-based models of the interplay between genetic and environmental factors in childhood allergy;Bornelöv;PLoS One,2013

3. The mechanisms, diagnosis, and management of severe asthma in adults;Holgate;Lancet,2006

4. Asthma: an epidemic of dysregulated immunity;Umetsu;Nat Immunol,2002

5. Immunological and inflammatory functions of the interleukin-1 family;Dinarello;Annu Rev Immunol,2009

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