Personalized medicine modality based on patient-derived xenografts from a malignant transformed GCTB harboring H3F3A G34W mutation

Author:

Yafei Jiang,Haoran Mu,Wenyan Jiang,Linghang Xue,Kai Tian,Gangyang Wang,Zhuoying Wang,Jing Han,Mengkai Yang,Yujie Tang,Yingqi Hua,Zhengdong Cai

Funder

National Natural Science Foundation of China

Shanghai Hospital Development Center

Publisher

Elsevier BV

Subject

Orthopedics and Sports Medicine

Reference24 articles.

1. Malignancy in giant cell tumor of bone;Bertoni;Cancer,2003

2. Histological and clinical characteristics of malignant giant cell tumor of bone;Gong;Virchows Arch : an international journal of pathology,2012

3. Organization WH: WHO Classification of Tumours of Soft Tissue and Bone;Fletcher,2013

4. Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone;Behjati;Nat Genet,2013

5. H3F3A (histone 3.3) G34W immunohistochemistry: a reliable marker defining benign and malignant giant cell tumor of bone;Amary;Am J Surg Pathol,2017

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