Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage – case study of Venetoclax-Reference-Cited by-同舟云学术

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Combining species specific in vitro & in silico models to predict in vivo food effect in a preclinical stage – case study of Venetoclax

Published:2021-07 Issue: Volume:162 Page:105840
ISSN:0928-0987
Container-title:European Journal of Pharmaceutical Sciences
language:en
Short-container-title:European Journal of Pharmaceutical Sciences

Author:

Henze Laura J.,Koehl Niklas J.,O'Shea Joseph P.,Holm René,Vertzoni Maria,Griffin Brendan T.

Funder

EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference27 articles.

1. Dissolution media simulating the proximal canine gastrointestinal tract in the fasted state;Arndt;Eur. J. Pharm. Biopharm.,2013

2. A review of drug solubility in human intestinal fluids: implications for the prediction of oral absorption;Augustijns;Eur. J. Pharm. Sci.,2014

3. Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs;Bergstrom;Eur. J. Pharm. Sci.,2014

4. Mechanistic physiologically based pharmacokinetic modeling of the dissolution and food effect of a biopharmaceutics classification system IV compound-the venetoclax story;Emami Riedmaier,;J. Pharm. Sci.,2018

5. Food-effect bioavailability and fed bioequivalence studies: guidance for industry;FDA,2002

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1. Application of physiologically based pharmacokinetics modeling in the research of small-molecule targeted anti-cancer drugs;Cancer Chemotherapy and Pharmacology;2023-07-19

2. Physiologically Based Pharmacokinetic (PBPK) Modeling Application on Food Effect Assessment;AAPS Introductions in the Pharmaceutical Sciences;2023

3. Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series;Pharmaceutics;2022-05-07

4. Bio-enabling strategies to mitigate the pharmaceutical food effect: A mini review;International Journal of Pharmaceutics;2022-05

5. Mucin-Protected Caco-2 Assay to Study Drug Permeation in the Presence of Complex Biorelevant Media;Pharmaceutics;2022-03-24

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