Effect of phosphorylation on the structural dynamics, thermal stability of human dopamine transporter: A simulation study using normal modes, molecular dynamics and Markov State Model

Author:

Quiroz R.C.N.,Philot E.A.,General I.J.,Perahia D.,Scott A.L.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

FAPESP

Publisher

Elsevier BV

Subject

Materials Chemistry,Computer Graphics and Computer-Aided Design,Physical and Theoretical Chemistry,Spectroscopy

Reference73 articles.

1. Interaction between dopamine and its transporter: role of intracellular sodium ions and membrane;Chen;potential,2004

2. Phosphorylation of dopamine transporter serine 7 modulates cocaine analog binding;Moritz;J. Biol. Chem.,2013

3. Missense dopamine transporter mutations associate with adult parkinsonism and ADHD;Hansen;J. Clin. Invest.,2014

4. iPSC modeling of young-onset Parkinson's disease reveals a molecular signature of disease and novel therapeutic candidates;Laperle;Nat. Med.,2020

5. Effects of the dopamine transporter gene on striatal functional connectivity in youths with attention;Shang;deficit/hyperactivity disorder,2021

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