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Arsenic trioxide (ATO) up-regulates cytochrome P450 1A (CYP1A) enzymes in murine hepatoma Hepa-1c1c7 cell line

  • Published:2023-08 Issue: Volume:101 Page:104214
  • ISSN:1382-6689
  • Container-title:Environmental Toxicology and Pharmacology
  • language:en
  • Short-container-title:Environmental Toxicology and Pharmacology

Author:

El-Ghiaty Mahmoud A.,Alqahtani Mohammed A.,El-Kadi Ayman O.S.

Funder

Natural Sciences and Engineering Research Council of Canada

Alberta Innovates

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference36 articles.

1. Arsenic trioxide-mediated oxidative stress and genotoxicity in human hepatocellular carcinoma cells;Alarifi;OncoTargets Ther.,2013

2. Mercury and methylmercury differentially modulate hepatic cytochrome P450 1A1 and 1A2 in vivo and in vitro;Alqahtani;J. Biochem. Mol. Toxicol.,2023

3. Differential modulation of cytochrome P450 1a1 by arsenite in vivo and in vitro in C57BL/6 mice;Anwar-Mohamed;Free Radic. Biol. Med.,2013

4. Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms;Anwar-Mohamed;Free Radic. Biol. Med.,2014

5. ATSDR, 2007. Toxicological profile for arsenic. Agency for Toxic Substances and Disease Registry, Atlanta.

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