Astragalus polysaccharide inhibits isoprenaline-induced cardiac hypertrophy via suppressing Ca2+-mediated calcineurin/NFATc3 and CaMKII signaling cascades

Author:

Dai Hongliang,Jia Guizhi,Liu Xin,Liu Zhining,Wang Hongxin

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,General Medicine

Reference49 articles.

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3. The critical role of Astragalus polysaccharides for the improvement of PPARalpha [correction of PPRAalpha]-mediated lipotoxicity in diabetic cardiomyopathy;Chen;PLoS ONE,2012

4. Beneficial effects of astragalus polysaccharides treatment on cardiac chymase activities and cardiomyopathy in diabetic hamsters;Chen;Acta Diabetol.,2010

5. Ca2+ oscillation frequency decoding in cardiac cell hypertrophy: role of calcineurin/NFAT as Ca2+ signal integrators;Colella;Proc. Natl. Acad. Sci. U. S. A.,2008

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