Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes 1 1Abbreviations: ADM, adriamycin; VP16, etoposide; Topo, topoisomerase; kDNA, knetoplast DNA; HCPT, hydrocamptothecin; SC, supercoiled form; RLX, relaxed form; LNR, linear form; and NC, nicked form.-Reference-Cited by-同舟云学术

Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes 1 1Abbreviations: ADM, adriamycin; VP16, etoposide; Topo, topoisomerase; kDNA, knetoplast DNA; HCPT, hydrocamptothecin; SC, supercoiled form; RLX, relaxed form; LNR, linear form; and NC, nicked form.

Published:2001-09 Issue:6 Volume:62 Page:733-741
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Meng Ling-hua,Zhang Jin-shen,Ding Jian

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference34 articles.

1. Study on the chemical constituents of salvia prionitis;Yang;Acta Bot Sinica,1988

2. A new diterpenoid quinone dehydromiltirone;Lin;Acta Pharm Sinica,1988

3. Structural elucidation of salpriolactone;Huang;Acta Bot Sinica,1990

4. A new diterpenoid quinone supriparaquinone;Lin;Acta Pharm Sinica,1990

5. In vitro cytotoxicity of salvicine, a novel diterpenoid quinone;Qing;Acta Pharm Sinica,1999

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