The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Author:

Franke Thomas F,Yang Sung-Il,Chan Tung O,Datta Ketaki,Kazlauskas Andrius,Morrison Deborah K,Kaplan David R,Tsichlis Philip N

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference31 articles.

1. The proteins encoded by v-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential;Ahmed;Oncogene,1993

2. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region;Bellacosa;Science,1991

3. Structure, expressioon chromosomal mapping of c-akt: relationship to v-akt and its implications;Bellacosa;Oncogene,1993

4. AKT2, a putative oncogene encoding a member of a subfamily of protein serine/threonine protein kinases, is amplified in human ovarian carcinomas;Cheng,1992

5. D-myo-inositol 1,4,5-trisphosphate inhibits binding of phospholipase C-δ1 to bilayer membranes;Cifuentes;J. Biol. Chem.,1994

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