Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

Author:

Schinkel A.H.,Smit J.J.M.,van Tellingen O.,Beijnen J.H.,Wagenaar E.,van Deemter L.,Mol C.A.A.M.,van der Valk M.A.,Robanus-Maandag E.C.,te Riele H.P.J.,Berns A.J.M.,Borst P.

Publisher

Elsevier BV

Subject

General Biochemistry, Genetics and Molecular Biology

Reference58 articles.

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3. Production and analysis of chimeric mice;Bradley,1987

4. Sex-dependent and independent expression of the P-glycoprotein isoforms in Chinese hamster;Bradley;J. Cell. Physiol.,1990

5. The blood-brain barrier: transport across the cerebral endothelium;Bradbury;Circ. Res.,1985

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