Idiopathic Inflammatory Bowel Disease in Cats: Rational Treatment Selection

Abstract

Practical relevance Inflammatory bowel disease (IBD) is a common diagnosis in cats with chronic gastrointestinal signs. Its management presents clinical challenges, not least because rational therapy relies on a definitive diagnosis, and current understanding of the underlying pathogenesis has, to date, limited the development of specific therapies. The mainstays of treatment remain dietary manipulation and immunosuppressive therapy, but treatment failures are not uncommon. A logical clinical approach is important and there are a number of alternative or adjunctive treatments that can prove useful in refractory cases. Evidence base This article draws on data from clinical trials in humans, in vitro studies, prospective and retrospective studies in cats with naturally occurring IBD, and clinical experience to discuss the work-up and treatment selection for cats with idiopathic IBD. Patient group IBD affects young adult to geriatric cats of both sexes. Audience Companion animal and feline practitioners are at the front line when it comes to managing these often challenging cases.