Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding

Author:

Aung Mie Mie,Griffin Graeme,Huffman John W,Wu Ming-Jung,Keel Cheryl,Yang Bin,Showalter Vincent M,Abood Mary E,Martin Billy R

Publisher

Elsevier BV

Subject

Pharmacology (medical),Psychiatry and Mental health,Pharmacology,Toxicology

Reference30 articles.

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3. Relationship between the inhibition constant (Ki) and the concentration of inhibitor which causes 50% inhibition (IC50) in an enzymatic reaction;Cheng;Biochem. Pharmacol.,1973

4. Aminoalkylindole analogues: cannabimimetic activity of a class of compounds structurally distinct from Δ9-THC;Compton;J. Pharmacol. Exp. Ther.,1992

5. Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities;Compton;J. Pharmacol. Exp. Ther.,1993

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