A ROS-mediated mitochondrial pathway and Nrf2 pathway activation are involved in BDE-47 induced apoptosis in Neuro-2a cells

Author:

Chen Hongmei,Tang Xuexi,Zhou Bin,Zhou Zhongyuan,Xu Ningning,Wang YouORCID

Funder

National Natural Science Foundation of China

Joint Fund of the National Natural Science Foundation of China and Shandong Province

China Postdoctoral Science Foundation

Publisher

Elsevier BV

Subject

General Medicine,General Chemistry,Environmental Chemistry,Environmental Engineering,Pollution,Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference31 articles.

1. The combined effects of BDE47 and BaP on oxidatively generated DNA damage in LO2 cells and the possible molecular mechanism;An;Mutat. Res.,2011

2. Low-dose treatment with polybrominated diphenyl ethers (PBDEs) induce altered characteristics in MCF-7 cells;Barber;Mutagenesis,2006

3. Cytotoxicity and apoptosis induction in Neuro-2a cells of BDE-47 and BDE-209;Chen;WIT Trans. Biomed. Health,2015

4. Mechanism of Deca-BDE-induced apoptosis in Neuro-2a cells: role of death-receptor pathway and reactive oxygen species-mediated mitochondrial pathway;Chen;J. Environ. Sci.,2016

5. Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defense in the HL-60 cell monocytic differentiation;Chen;Cell Biol. Int.,2013

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