Transcriptome-wide association study and Mendelian randomization in pancreatic cancer identifies susceptibility genes and causal relationships with type 2 diabetes and venous thromboembolism

Author:

Tan Marcus C.B.ORCID,Isom Chelsea A.,Liu Yangzi,Trégouët David-Alexandre,Lindstrom Sara,Wang Lu,Smith Erin,Gordon William,Van Hylckama Vlieg Astrid,De Andrade Mariza,Brody Jennifer,Pattee Jack,Haessler Jeffrey,Brumpton Ben,Chasman Daniel,Suchon Pierre,Chen Ming-Huei,Turman Constance,Germain Marine,Wiggins Kerri,MacDonald James,Braekkan Sigrid,Armasu Sebastian,Pankratz Nathan,Jackson Rabecca,Nielsen Jonas,Giulianini Franco,Puurunen Marja,Ibrahim Manal,Heckbert Susan,Bammler Theo,Frazer Kelly,McCauley Bryan,Taylor Kent,Pankow James,Reiner Alexander,Gabrielsen Maiken,Deleuze Jean-François,O'Donnell Chris,Kim Jihye,McKnight Barbara,Kraft Peter,Hansen John-Bjarne,Rosendaal Frits,Heit John,Psaty Bruce,Tang Weihong,Kooperberg Charles,Hveem Kristian,Ridker Paul,Morange Pierre-Emmanuel,Johnson Andrew,Kabrhel Christopher,Trégouët David-Alexandre,Smith Nicholas,Wu Lang,Zhou Dan,Gamazon Eric R.ORCID

Publisher

Elsevier BV

Reference71 articles.

1. Cancer statistics, 2023;Siegel;CA Cancer J Clin,2023

2. The multicenter cancer of pancreas screening study: impact on stage and survival;Dbouk;J Clin Oncol,2022

3. Prevalence and clinical profile of pancreatic cancer-associated diabetes mellitus;Pannala;Gastroenterology,2008

4. Diabetes type 2 and pancreatic cancer: a history unfolding;De Souza;JOP,2016

5. Incidence of venous thromboembolism in patients with cancer – a cohort study using linked United Kingdom databases;Walker;Eur J Cancer,2013

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