Mendelian randomization and clinical trial evidence supports TYK2 inhibition as a therapeutic target for autoimmune diseases
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference53 articles.
1. POS1042 efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 (TYK2) inhibitor, compared with placebo and apremilast in moderate to severe plaque psoriasis: results from the phase 3 poetyk PSO-1 study;Armstrong;Ann Rheum Dis,2021
2. Phase 2 trial of selective tyrosine kinase 2 inhibition in psoriasis;Papp;N Engl J Med,2018
3. Efficacy and safety of upadacitinib in a randomized trial of patients with Crohn's disease;Sandborn;Gastroenterology,2020
4. Baricitinib versus placebo or adalimumab in rheumatoid arthritis;Taylor;N Engl J Med,2017
5. Effects of sotagliflozin added to insulin in patients with type 1 diabetes;Garg;N Engl J Med,2017
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