Biotransformation and transplacental transfer of the anti-viral remdesivir and predominant metabolite, GS-441524 in pregnant rats
Author:
Publisher
Elsevier BV
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference36 articles.
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3. Potency and pharmacokinetics of GS-441524 derivatives against SARS-CoV-2;Wei;Bioorg Med Chem,2021
4. Remdesivir for the Treatment of Covid-19 - Final Report;Beigel;N Engl J Med,2020
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1. The anti-COVID-19 drug Paxlovid crosses biological barriers of the placenta and brain in rats;npj Viruses;2024-01-24
2. Pharmacokinetic analysis of placental transfer of ritonavir as a component of paxlovid using microdialysis in pregnant rats;Heliyon;2024-01
3. Transporter modulation of molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-brain barrier in a rat;Communications Medicine;2023-10-19
4. Transfer and biotransformation of the COVID-19 prodrug molnupiravir and its metabolite β-D-N4-hydroxycytidine across the blood-placenta barrier;eBioMedicine;2023-09
5. Oral GS-441524 derivatives: Next-generation inhibitors of SARS‐CoV‐2 RNA‐dependent RNA polymerase;Frontiers in Immunology;2022-12-06
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