Inflammatory biomarkers in Alzheimer's disease plasma

Author:

Morgan Angharad R.1,Touchard Samuel1,Leckey Claire1,O'Hagan Caroline1,Nevado‐Holgado Alejo J.2,Barkhof Frederik34,Bertram Lars5,Blin Olivier6,Bos Isabelle7,Dobricic Valerija8,Engelborghs Sebastiaan910,Frisoni Giovanni1112,Frölich Lutz13,Gabel Silvey14,Johannsen Peter15,Kettunen Petronella16,Kłoszewska Iwona17,Legido‐Quigley Cristina418,Lleó Alberto19,Martinez‐Lage Pablo20,Mecocci Patrizia21,Meersmans Karen14,Molinuevo José Luis22,Peyratout Gwendoline23,Popp Julius24,Richardson Jill25,Sala Isabel26,Scheltens Philip27,Streffer Johannes28,Soininen Hikka29,Tainta‐Cuezva Mikel30,Teunissen Charlotte31,Tsolaki Magda32,Vandenberghe Rik33,Visser Pieter Jelle34,Vos Stephanie7,Wahlund Lars‐Olof35,Wallin Anders36,Westwood Sarah2,Zetterberg Henrik37383940,Lovestone Simon2,Morgan B. Paul1, ,

Affiliation:

1. Systems Immunity Research Institute and UK Dementia Research Institute CardiffSchool of MedicineCardiff UniversityCardiffUK

2. Department of PsychiatryUniversity of OxfordOxfordUK

3. Department of Radiology and Nuclear MedicineVU University MedicalAmsterdamthe Netherlands

4. UCL Institutes of Neurology and Healthcare EngineeringUniversity College LondonLondonUK

5. Max Planck Institute for Molecular GeneticsBerlinGermany

6. Aix‐Marseille UniversityAPHMInstitute Neurosci SystemPharmacologyMarseilleFrance

7. Alzheimer Centrum LimburgMaastricht UniversityMaastrichtthe Netherlands

8. Lübeck Interdisciplinary Platform for Genome AnalyticsUniversity of LübeckLübeckGermany

9. Department of NeurologyHospital Network Antwerp (ZNA)AntwerpBelgium

10. Reference Center for Biological Markers of DementiaInstitute Born‐BungeAntwerpBelgium

11. University of GenevaGenevaSwitzerland

12. IRCCS Istituto Centro San Giovanni di Dio FatebenefratelliBresciaItaly

13. Department of Geriatric PsychiatryZentralinstitut für Seelische GesundheitUniversity of HeidelbergMannheimGermany

14. Department of NeurosciencesLaboratory for Cognitive NeurologyKU LeuvenLeuvenBelgium

15. Division of Clinical GeriatricsDepartment of NeurobiologyCaring Sciences and SocietyKarolinska InstitutetStockholmSweden

16. University of GothenburgInstitute of Neuroscience and PhysiologyGothenburgSweden

17. Department of Old Age Psychiatry & Psychotic DisordersMedical University of LodzLodzPoland

18. School of Public HealthImperial College LondonLondonUK

19. Department of NeurologyHospital de la Santa Creu i Sant PauBarcelonaSpain

20. CITA‐Alzheimer FoundationSan SebastianSpain

21. Department of MedicineInstitute of Gerontology and GeriatricsUniversity of PerugiaPerugiaItaly

22. Barcelona Beta Brain Research CenterUnversitat Pompeu FabraBarcelonaSpain

23. Department of PsychiatryOld Age PsychiatryLausanne University HospitalLausanneSwitzerland

24. Hopitaux Universitaires Geneve and Universite de GeneveGenevaSwitzerland

25. Neurosciences Therapeutic AreaGlaxoSmithKline R&DStevenageUK

26. Memory UnitNeurology DepartmentHospital de la Santa Creu i Sant PauBarcelonaSpain

27. Alzheimer CenterAmsterdam University Medical CentersVrije UniversiteitAmsterdamthe Netherlands

28. Reference Center for Biological Markers of Dementia (BIODEM)Institute Born‐BungeUniversity of AntwerpAntwerpBelgium

29. Institute of Clinical MedicineNeurologyUniversity of Eastern FinlandKuopioFinland

30. Center for Research and Advanced TherapiesCITA‐Alzheimer FoundationSan SebastianSpain

31. University Hospital LeuvenLeuvenBelgium

32. 1st Department of NeurologyAHEPA University HospitalMakedoniaThessalonikiGreece

33. Department of Clinical ChemistryNeurochemistry labAmsterdam University Medical CentersAmsterdamthe Netherlands

34. Department of Psychiatry & NeuropsychologySchool for Mental Health and NeuroscienceMaastricht UniversityMaastrichtthe Netherlands

35. NVS‐DepartmentSection of Clinical GeriatricsKarolinska InstitutetHuddingeSweden

36. Section for Psychiatry and NeurochemistryInstitute of Neuroscience and PhysiologyUniversity of Gothenburg Sahlgrenska AcademyGothenburgSweden

37. Clinical Neurochemistry LabInstitute of Neuroscience and PhysiologySahlgrenska University HospitalMölndalSweden

38. Institute of Neuroscience and PhysiologyDepartment of Psychiatry and NeurochemistryUniversity of GothenburgMölndalSweden

39. Department of Molecular NeuroscienceUCL Institute of NeurologyLondonUK

40. UK Dementia Research InstituteLondonUK

Funder

Wellcome Trust

Janssen Pharmaceutica N.V.

ADx Neurosciences

Swiss National Science Foundation

Fujirebio Europe

Lilly

Ono Pharma

Nestlé Institute of Health Sciences

Piramal

Roche

S.V

ZonMw

Health Research

Alzheimer's Association

NIHR

National Institute for Health Research

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Clinical Neurology,Developmental Neuroscience,Health Policy,Epidemiology

Reference52 articles.

1. The AD-CSF-Index Discriminates Alzheimer's Disease Patients from Healthy Controls: A Validation Study

2. The role of biomarkers and imaging in the clinical diagnosis of dementia;Bayer A.J.;Age Ageing,2018

3. CSF tau and the CSF tau/ABeta ratio for the diagnosis of Alzheimer's disease dementia and other dementias in people with mild cognitive impairment (MCI);Ritchie C.;Cochrane Database Syst Rev,2017

4. Proteome-based plasma biomarkers for Alzheimer's disease

5. Plasma biomarkers for mild cognitive impairment and Alzheimer's disease

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