Platycodin D (PD) attenuates myocardial apoptosis mediated by JNK-SIRT1-HSF1-IGF-IIR-Caspase-3 signaling in hypertensive conditions

Author:

Lin Yuan-Chuan,Lin Yu-Chen,Kuo Wei-Wen,Shen Chia-Yao,Chen Yu-Feng,Lin Yueh-Min,Ho Tsung-Jung,Padma V. Vijaya,Huang Chih-YangORCID,Huang Chih-Yang

Funder

Ministry of Health and Welfare, Taiwan

Publisher

Elsevier BV

Subject

Nutrition and Dietetics,Medicine (miscellaneous),Food Science

Reference23 articles.

1. Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways;Chun;Chem. Biol. Interact.,2013

2. Caspase activation pathways: Some recent progress;Cullen;Cell Death Differ.,2009

3. Caspase-3 in the central nervous system: Beyond apoptosis;D'Amelio;Trends Neurosci.,2012

4. Role of angiotensin II in blood pressure regulation and in the pathophysiology of cardiovascular disorders;Fyhrquist;J. Hum. Hypertens.,1995

5. Mannose 6-phosphate receptors: New twists in the tale;Ghosh;Nat. Rev. Mol. Cell Biol.,2003

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