Oligosaccharides of Ophiopogon japonicus ameliorate insulin resistance and glucolipid metabolism in HFD/STZ-induced T2DM rats and IR-HepG2 cells via activation of the IRS-1/PI3K/AKT/GSK-3β pathway-Reference-Cited by-同舟云学术

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Oligosaccharides of Ophiopogon japonicus ameliorate insulin resistance and glucolipid metabolism in HFD/STZ-induced T2DM rats and IR-HepG2 cells via activation of the IRS-1/PI3K/AKT/GSK-3β pathway

Published:2024-09 Issue: Volume:120 Page:106368
ISSN:1756-4646
Container-title:Journal of Functional Foods
language:en
Short-container-title:Journal of Functional Foods

Author:

Chen Baoting,Li Zilin,Fang Jia,Liu Yiming,Lin Aihua^ORCID

Funder

Key Science and Technology Research Project in Jiangxi Province Department of Education

School of Traditional Chinese Medicine, Guangdong Pharmaceutical University

Affiliated Hospital of Southwest Medical University

Guangzhou Science, Technology and Innovation Commission

Publisher

Elsevier BV

Reference41 articles.

1. Polyherbal formulation improves glucose-lipid metabolism and prevent hepatotoxicity in streptozotocin-induced diabetic rats: Plausible role of IRS-PI3K-Akt-GLUT2 Signaling;Abdul Haye;Pharmacognosy magazine,2022

2. Type 2 diabetes;Ahmad;Lancet,2022

3. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway;Alaaeldin;Molecules (Basel Switzerland),2021

4. Antidiabetic effect of sciadonic acid on type 2 diabetic mice through activating the PI3K-AKT signaling pathway and altering intestinal flora;Chen;Frontiers in nutrition,2022

5. Ophiopogon japonicus–A phytochemical, ethnomedicinal and pharmacological review;Chen;Journal of Ethnopharmacology,2016

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