Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity

Author:

Hopperton Kathryn E.,Duncan Robin E.,Bazinet Richard P.,Archer Michael C.

Publisher

Elsevier BV

Subject

Cell Biology

Reference42 articles.

1. Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis;Menendez;Nat. Rev. Cancer,2007

2. Fatty-acid biosynthesis in man, a pathway of minor importance. Purification, optimal assay conditions, and organ distribution of fatty-acid synthase;Weiss;Biol. Chem. Hoppe-Seyler,1986

3. Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patients;Wang;Cancer Lett.,2001

4. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB;Menendez;Int. J. Oncol.,2004

5. Fatty acid synthase (FAS) predictive strength in poorly differentiated early breast carcinomas;Alo;Tumori,1999

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