miR-338-3p confers 5-fluorouracil resistance in p53 mutant colon cancer cells by targeting the mammalian target of rapamycin

Author:

Han Jia,Li Jie,Tang Kaijie,Zhang Huahua,Guo Bo,Hou Ni,Huang Chen

Funder

National Natural Science Foundation of China

Scientific Research Foundation for Returned Overseas Chinese Scholars, State Education Ministry

Shaanxi Province Scientific Research and Sharing Platform Construction Project

Publisher

Elsevier BV

Subject

Cell Biology

Reference34 articles.

1. Global cancer statistics, 2012;Torre;CA - Cancer J. Clin.,2015

2. The association of TP53 mutations with the resistance of colorectal carcinoma to the insulin-like growth factor-1 receptor inhibitor picropodophyllin;Wang;BMC Cancer,2013

3. 5-fluorouracil: mechanisms of action and clinical strategies;Longley;Nat. Rev. Cancer,2003

4. Chronic exposure of colorectal cancer cells in culture to fluoropyrimidine analogs induces thymidylate synthase and suppressesp53. A molecular explanation for the mechanism of 5-FU resistance;Subbarayan;Anticancer Res.,2010

5. The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells;Huang;Cancer Biol. Ther.,2009

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3