Plasma neurofilament light associates with Alzheimer's disease metabolic decline in amyloid‐positive individuals

Author:

Benedet Andréa L.1234,Ashton Nicholas J.56778,Pascoal Tharick A.12,Leuzy Antoine910,Mathotaarachchi Sulantha12,Kang Min S.12,Therriault Joseph12,Savard Melissa12,Chamoun Mira12,Schöll Michael56779,Zimmer Eduardo R.11121314,Gauthier Serge1112,Labbe Aurélie1516,Zetterberg Henrik56171819,Blennow Kaj561718,Neto Pedro R.12202122,

Affiliation:

1. Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, McGill UniversityMontrealQuebecCanada

2. Translational Neuroimaging Laboratory, McGill Centre for Studies in Aging, McGill UniversityMontrealQCCanada

3. CAPES Foundation, Ministry of Education of BrazilBrasíliaBrazil

4. CAPES Foundation, Ministry of Education of BrazilBrasiliaBrazil

5. Department of Psychiatry and NeurochemistryInstitute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of GothenburgMölndalSweden

6. Department of Psychiatry and NeurochemistryInstitute of Neuroscience & Physiology, the Sahlgrenska Academy at the University of GothenburgMolndalSweden

7. Wallenberg Centre for Molecular and Translational MedicineUniversity of GothenburgGothenburgSweden

8. King's College London, Institute of PsychiatryPsychology and NeuroscienceMaurice Wohl Institute Clinical Neuroscience InstituteLondonUK

9. Clinical Memory Research UnitDepartment of Clinical Sciences, MalmöLund UniversityLundSweden

10. Clinical Memory Research UnitDepartment of Clinical Sciences, MalmoLund UniversityLundSweden

11. Alzheimer's Disease Research UnitThe McGill University Research Centre for Studies in Aging, Montreal, McGill UniversityMontrealQuebecCanada

12. Alzheimer's Disease Research UnitThe McGill University Research Centre for Studies in Aging, Montreal, McGill UniversityMontrealQCCanada

13. Department of PharmacologyUniversidade Federal do Rio Grande do SulPorto AlegreBrazil

14. Departament of PharmacologyUniversidade Federal do Rio Grande do SulPorto AlegreBrazil

15. Department of Decision SciencesHEC MontrealMontrealQuebecCanada

16. Department of Decision SciencesHEC MontrealMontrealQCCanada

17. Clinical Neurochemistry Laboratory, Sahlgrenska University HospitalMölndalSweden

18. Clinical Neurochemistry Laboratory, Sahlgrenska University HospitalMolndalSweden

19. Department of Neurodegenerative DiseaseUCL Institute of NeurologyQueen SquareLondonUK

20. Montreal Neurological InstituteMontrealQuebecCanada

21. Montreal Neurological InstituteMontrealQCCanada

22. Department of Neurology and NeurosurgeryMcGill UniversityMontrealQuebecCanada

Funder

Alzheimer's Disease Neuroimaging Initiative

National Institutes of Health

U.S. Department of Defense

National Institute on Aging

National Institute of Biomedical Imaging and Bioengineering

AbbVie

Alzheimer's Association

Alzheimer's Drug Discovery Foundation

BioClinica

Biogen

Bristol-Myers Squibb

Eisai

Eli Lilly and Company

Roche

Genentech

GE Healthcare

H. Lundbeck A/S

Meso Scale Diagnostics

Novartis Pharmaceuticals Corporation

Pfizer

Servier

Takeda Pharmaceutical Company

Canadian Institutes of Health Research

Weston Brain Institute

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Torsten Söderbergs Stiftelse

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul

Vetenskapsrådet

DOD

ADNI

Department of Defense

Araclon Biotech

BioClinica, Inc

Bristol-Myers Squibb Company

CereSpir, Inc

Cogstate

Elan Pharmaceuticals, Inc

EuroImmun

F. Hoffmann-La Roche Ltd

Genentech, Inc

Fujirebio

IXICO Ltd

Janssen Alzheimer Immunotherapy Research & Development, LLC

Johnson & Johnson Pharmaceutical Research & Development LLC

Lumosity

Lundbeck

Merck & Co, Inc

NeuroRx Research

Neurotrack Technologies

Pfizer Inc

Piramal Imaging

Transition Therapeutics

Alzecure

Canadian Consortium of Neurodegeneration in Aging

CAPES

Wallenberg Center for Molecular and Translational Medicine

Torsten Söderberg Foundation

CNPq

FAPERGS

Brazilian National Institute of Science and Technology in Excitotoxicity and Neuroprotection

SESRS–PPSUS

Swedish Research Council

European Research Council

Swedish State Support for Clinical Research

UK Dementia Research Institute

Fonds de la recherche en santé du Québec

Publisher

Wiley

Subject

Psychiatry and Mental health,Neurology (clinical)

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