Shikonin contributes to intestinal epithelial cell differentiation through PKM2/NRF2-mediated Polyol pathway

Author:

Huang Ling,Tang Xiufu,Yang FangYing,Pan Wenxu,Liang Xinhua,Xu Zhaohui,Cao Meiwan,Zhao Junhong,Chen Huan,Huang Jing,Chen Jiayu,Geng Lanlan,Xu Wanfu,Gong Sitang

Publisher

Elsevier BV

Reference44 articles.

1. Shikonin ameliorates experimental autoimmune encephalomyelitis (EAE) via immunomodulatory, anti-apoptotic and antioxidative activity;Nasrollahzadeh Sabet;J. Pharm. Pharmacol.,2020

2. Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome;Guo;Front. Physiol.,2020

3. Shikonin reduces hepatic fibrosis by inducing apoptosis and inhibiting autophagy via the platelet-activating factor-mitogen-activated protein kinase axis;Song;Exp. Ther. Med.,2021

4. Shikonin enhances the antitumor effect of cabazitaxel in prostate cancer stem cells and reverses cabazitaxel resistance by inhibiting ABCG2 and ALDH3A1;Wang;Am. J. Cancer Res.,2020

5. Shikonin inhibits prostate cancer cells metastasis by reducing matrix metalloproteinase-2/-9 expression via AKT/mTOR and ROS/ERK1/2 pathways;Chen;Int. Immunopharmacol.,2014

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