The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood–brain barrier in the pharmaceutical industry—Background and current status in the drug discovery process
Author:
Publisher
Elsevier BV
Subject
Pharmacology,Molecular Medicine,Physiology
Reference17 articles.
1. Bovine brain microvessel endothelial cell monolayers as a model system for the blood–brain barrier;Audus;Ann. N.Y. Acad. Sci.,1988
2. Functional expression of P-glycoprotein in an immortalised cell line of rat brain endothelial cells, RBE4;Begley;J. Neurochem.,1996
3. Increased vesicular transport and decreased mitochondrial content in blood–brain barrier endothelial cells during experimental autoimmune encephalomyelitis;Claudio;Am. J. Pathol.,1989
4. Evidence of persistent blood–brain barrier abnormalities in chronic-progressive multiple sclerosis;Claudio;Acta Neuropathol.,1995
5. An easier, reproducible and mass production method to study the blood–brain barrier in vitro;Dehouck;J. Neurochem.,1990
Cited by 46 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. A review on in vitro model of the blood-brain barrier (BBB) based on hCMEC/D3 cells;Journal of Controlled Release;2023-06
2. Lecithin and anionic lipids as an imitation of the lipid membrane in Parallel Artificial Membrane Permeation Assay (PAMPA) blood brain barrier Models;PROG NUTR;2020
3. From Adsorption to Covalent Bonding: Apolipoprotein E Functionalization of Polymeric Nanoparticles for Drug Delivery Across the Blood–Brain Barrier;Advanced Therapeutics;2020-07-26
4. Challenges and Strategies for Quantification of Drugs in the Brain: Current Scenario and Future Advancement;Critical Reviews in Analytical Chemistry;2020-07-20
5. Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization;Lab on a Chip;2020
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3