PHLPP and a Second Isoform, PHLPP2, Differentially Attenuate the Amplitude of Akt Signaling by Regulating Distinct Akt Isoforms
Author:
Publisher
Elsevier BV
Subject
Cell Biology,Molecular Biology
Reference42 articles.
1. Perturbations of the AKT signaling pathway in human cancer;Altomare;Oncogene,2005
2. Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors;Andjelkovic;Proc. Natl. Acad. Sci. USA,1996
3. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1;Biggs;Proc. Natl. Acad. Sci. USA,1999
4. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB;Biondi;EMBO J.,2001
5. Phosphorylation of protein kinase C-alpha on serine 657 controls the accumulation of active enzyme and contributes to its phosphatase-resistant state;Bornancin;J. Biol. Chem.,1997
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