Syntheses of prodrug-type phosphotriester oligonucleotides responsive to intracellular reducing environment for improvement of cell membrane permeability and nuclease resistance-Reference-Cited by-同舟云学术

Syntheses of prodrug-type phosphotriester oligonucleotides responsive to intracellular reducing environment for improvement of cell membrane permeability and nuclease resistance

Published:2017-07 Issue:14 Volume:27 Page:3135-3138
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hayashi Junsuke,Samezawa Yusuke,Ochi Yosuke,Wada Shun-ichi,Urata Hidehito

Funder

Grant-in-Aid for Young Scientists

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference27 articles.

1. The Role of Environmental Carcinogens, Viruses, and Genetic

2. Antisense technologies. Improvement through novel chemical modifications

3. The Medicinal Chemistry of Therapeutic Oligonucleotides

4. Oligodeoxynucleoside phosphorothioate stability in subcellular extracts, culture media, sera and cerebrospinal fluid

5. Oligodeoxynucleotide stability in subcellular extracts and culture media

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