Defining optimum lipophilicity and molecular weight ranges for drug candidates—Molecular weight dependent lower logD limits based on permeability
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference36 articles.
1. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
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4. The influence of drug-like concepts on decision-making in medicinal chemistry
5. Physiochemical drug properties associated with in vivo toxicological outcomes
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