2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors-Reference-Cited by-同舟云学术

2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors

Published:2013-09 Issue:17 Volume:23 Page:5014-5021
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Siu Michael,Pastor Richard,Liu Wendy,Barrett Kathy,Berry Megan,Blair Wade S.,Chang Christine,Chen Jacob Z.,Eigenbrot Charles,Ghilardi Nico,Gibbons Paul,He Haiying,Hurley Christopher A.,Kenny Jane R.,Cyrus Khojasteh S.,Le Hoa,Lee Leslie,Lyssikatos Joseph P.,Magnuson Steve,Pulk Rebecca,Tsui Vickie,Ultsch Mark,Xiao Yisong,Zhu Bing-yan,Sampath Deepak

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference25 articles.

1. The Janus kinases (Jaks)

2. Role of JAK2 in the pathogenesis and therapy of myeloproliferative disorders

3. X-inactivation–based clonality analysis and quantitative JAK2V617F assessment reveal a strong association between clonality and JAK2V617F in PV but not ET/MMM, and identifies a subset of JAK2V617F-negative ET and MMM patients with clonal hematopoiesis

4. A Gain-of-Function Mutation ofJAK2in Myeloproliferative Disorders

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