Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors-Reference-Cited by-同舟云学术

Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors

Published:2012-10 Issue:19 Volume:22 Page:6212-6217
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Jiao XianYun,Kopecky David J.,Liu JinSong,Liu JinQian,Jaen Juan C.,Cardozo Mario G.,Sharma Rajiv,Walker Nigel,Wesche Holger,Li Shyun,Farrelly Ellyn,Xiao Shou-Hua,Wang Zhulun,Kayser Frank

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference31 articles.

1. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

2. Cloning and Characterization of a Novel Cdc42-associated Tyrosine Kinase, ACK-2, from Bovine Brain

3. Purification and Enzyme Activity of ACK1

4. Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain

5. Overexpression of Arabidopsis ACK1 alters leaf morphology and retards growth and development

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