Elongation of the side chain by linear alkyl groups increases the potency of salacinol, a potent α-glucosidase inhibitor from the Ayurvedic traditional medicine “Salacia,” against human intestinal maltase
Author:
Publisher
Elsevier BV
Subject
Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry
Reference54 articles.
1. Salacinol, potent antidiabetic principle with unique thiosugar sulfonium sulfate structure from the Ayurvedic traditional medicine Salacia reticulata in Sri Lanka and India
2. Absolute Stereostructure of Potent α-Glucosidase Inhibitor, Salacinol, with Unique Thiosugar Sulfonium Sulfate Inner Salt Structure from Salacia reticulata
3. Kotalanol, a Potent a-Glucosidase Inhibitor with Thiosugar Sulfonium Sulfate Structure, from Antidiabetic Ayurvedic Medicine Salacia reticulata.
4. Salaprionol and Ponkoranol with Thiosugar Sulfonium Sulfate Structure from Salacia prinoides and a-Glucosidase Inhibitory Activity of Ponkoranol and Kotalanol Desulfate
5. Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases
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1. Salacia reticulata: An Integrative Review of Its Antioxidant, Lipid-Lowering, and Glucose-Regulating Properties in Diabetes and Obesity;The Natural Products Journal;2024-04-24
2. Role of the thiosugar ring in the inhibitory activity of salacinol, a potent natural α-glucosidase inhibitor;RSC Advances;2024
3. Pharmaceutical Food Science: Search for Bio-Functional Molecules Obtained from Natural Resources to Prevent and Ameliorate Lifestyle Diseases;Chemical and Pharmaceutical Bulletin;2023-10-01
4. Synthetic studies on naturally occurring sulfonium-type α-glucosidase inhibitors: progress and perspective;Journal of Carbohydrate Chemistry;2022-06-13
5. A review of antidiabetic active thiosugar sulfoniums, salacinol and neokotalanol, from plants of the genus Salacia;Journal of Natural Medicines;2021-04-26
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